Product Introduction
This product is used to detect concentration of Myoglobin (Myo) in human serum and plasma. Myoglobin is an iron- and oxygen-binding protein found in the muscle tissue of vertebrates. In human body, myoglobin is only found in the bloodstream after muscle injury. While muscle injury occurs, myoglobin could be released into blood rapidly and exceeds the normal level in about 1 hour. Thus myoglobin is a sensitive marker for muscle injury, making it a potential marker for heart attack in patients with chest pain. However, elevated myoglobin has low specificity for acute myocardial infarction (AMI) and thus CK-MB, cardiac Troponin, ECG, and clinical signs should be taken into account to make the diagnosis[1- 3].
Myo is the earliest marker after AMI, and it is a sensitive and accurate indicator to judge whether there is reperfusion in thrombolytic therapy. Biotime Myo test kit is mainly used to detect Myo quantity in human serum and plasma samples.
Advantage
The sample requirement is low, only 10μL of serum/plasma is required
Clinical significance
One of the most sensitive indicators to detect early AMI, exclude early AMI negative
Application
ICU, Respiratory Medicine, Emergency Department, Cardiology, Laboratory, Emergency Car
Reference
1. Le Tao. The clinical application and evaluation of the triad rapid diagnosis to myocardial infarction. Journal of Chinese Clinical Medicine. 2005. 140: 15239- 15240
2. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction[J]. J Am Coll Cardiol. 2000. 36(3):959-969.
3. Levinson SS. The nature of heterophilic antibodies and their role in immunoassay interference. [J]. Clinical Immunoassay. 1992. 15:108-15.
